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| Atlanta Silverbacks* | 3 - 2 | Rochester Raging Rhinos | ||
| 17.09.2007 | Rochester Raging Rhinos | 1-1 | Atlanta Silverbacks |  |
| 15.09.2007 | Atlanta Silverbacks | 2-1 | Rochester Raging Rhinos | |
| Montreal Impact | 3 - 5 | Puerto Rico Islanders* | ||
| 17.09.2007 | Puerto Rico Islanders | 3-0 | Montreal Impact | |
| 15.09.2007 | Montreal Impact | 3-2 | Puerto Rico Islanders | |
| Vancouver Whitecaps | 1 - 3 | Portland Timbers* | ||
| 17.09.2007 | Portland Timbers | 3-0 | Vancouver Whitecaps | |
| 15.09.2007 | Vancouver Whitecaps | 1-0 | Portland Timbers | |
| Carolina Railhawks | 0 - 3 | Seattle Sounders* | ||
| 17.09.2007 | Seattle Sounders | 1-0 | Carolina Railhawks | |
| 15.09.2007 | Carolina Railhawks | 0-2 | Seattle Sounders | |