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| Colorado Rapids | 2 - 2 | FC Dallas | ||
| 30.10.2005 | FC Dallas | 2-2 p.4-5 |
Colorado Rapids |  |
| 23.10.2005 | Colorado Rapids | 0-0 | FC Dallas | |
| Chicago Fire | 4 - 0 | DC United | ||
| 30.10.2005 | DC United | 0-4 | Chicago Fire | |
| 22.10.2005 | Chicago Fire | 0-0 | DC United | |
| New York Red Bulls | 2 - 3 | New England Revolution | ||
| 30.10.2005 | New England Revolution | 3-1 | New York Red Bulls | |
| 23.10.2005 | New York Red Bulls | 1-0 | New England Revolution | |
| Los Angeles Galaxy | 4 - 2 | San Jose Earthquake | ||
| 30.10.2005 | San Jose Earthquake | 1-1 | Los Angeles Galaxy | |
| 23.10.2005 | Los Angeles Galaxy | 3-1 | San Jose Earthquake | |