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| 03.02.2025 | D1 | Santos Laguna | 0-2 | Club Puebla | |
| 06.07.2024 | D1 | Club Puebla | 1-0 | Santos Laguna | |
| 31.01.2024 | D1 | Santos Laguna | 3-0 | Club Puebla | |
| 08.07.2023 | D1 | Club Puebla | 2-3 | Santos Laguna | |
| 27.02.2023 | D1 | Santos Laguna | 3-2 | Club Puebla | |
| 09.07.2022 | D1 | Club Puebla | 1-0 | Santos Laguna |
| GP | W | D | L | GF | GA | +/- | |
| home | 6 | 1 | 1 | 4 | 4 | 9 | -5 |
| away | 6 | 1 | 1 | 4 | 6 | 10 | -4 |
| total | 6 | 0 | 1 | 5 | 2 | 12 | -10 |
| Puebla win | 18.00% | 9 |
| draw | 40.00% | 20 |
| Puebla lose | 42.00% | 21 |
| GP | W | D | L | GF | GA | +/- | |
| home | 6 | 2 | 0 | 4 | 7 | 11 | -4 |
| away | 6 | 0 | 1 | 5 | 6 | 14 | -8 |
| total | 6 | 2 | 0 | 4 | 9 | 13 | -4 |
| Santos Laguna win | 42.00% | 21 |
| draw | 40.00% | 20 |
| Santos Laguna lose | 18.00% | 9 |
| 05.04.2025 | D1 | Club Puebla | 0-0 | Tigres UANL |  |
| 30.03.2025 | D1 | FC Juárez | 2-0 | Club Puebla |  |
| 15.03.2025 | D1 | Club Puebla | 0-3 | Deportivo Toluca | |
| 08.03.2025 | D1 | Club Puebla | 1-3 | UNAM Pumas | |
| 02.03.2025 | D1 | Querétaro FC | 2-0 | Club Puebla | |
| 27.02.2025 | D1 | Pachuca CF | 2-1 | Club Puebla | |
| 07.04.2025 | D1 | Deportivo Toluca | 2-1 | Santos Laguna | |
| 31.03.2025 | D1 | Santos Laguna | 2-3 | Atlético San Luis | |
| 16.03.2025 | D1 | Tigres UANL | 3-0 | Santos Laguna | |
| 10.03.2025 | D1 | Santos Laguna | 2-1 | Club León |  |
| 03.03.2025 | D1 | CF Monterrey | 4-2 | Santos Laguna | |
| 24.02.2025 | D1 | Santos Laguna | 2-0 | Club Atlas | |
| over 2.5 | 44.44% | 16 |
| under 2.5 | 55.56% | 20 |
| over 2.5 | 47.50% | 19 |
| under 2.5 | 52.50% | 21 |
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